Sentence examples for defective alignment from inspiring English sources

We demonstrated that knockdown of myosin heavy chain 1 (myhc1) resulted in sarcomeric defects in the thick and thin filaments and defective alignment of Z-lines.

In these cells, lack of Prox1 function lead to subtle phenotypic alterations; e.g., defective alignment of hair cells and supporting cells (Fig. 5) However, major pathfinding defects were identified in Type II spiral ganglion fibers.

As expected, CENP-E silencing produced defective chromosome alignment with numerous chromosomes located in the polar region (Figure 7B), in accordance with its role in chromosome congression [52], [54].

The absence of Nek2 kinase activity triggers defective chromosome alignment and cell death.

Due to the loss of its anchorage via plectin and the resulting defective lateral alignment of myofibrils, the desmin IF network can no longer keep sarcomeres in register.

In addition, the defective cell alignment and suture formation in the lens of Vangl2 and Celsr1 mutant mice (both are genes that participate in the PCP pathway) indicate that this process is regulated by PCP signalling (Sugiyama et al., 2010).

The timing of these events may play a central role in selecting the central pathways leading to cell death; however the data are consistent with the notion that concerted transcriptional downregulation of genes responsible for spindle complex assembly and midbody formation by deacetylase inhibitors leads to abrogated abscission or defective chromosome alignment and cell death.

Most abnormalities result from defective migration and alignment of the CC relative to the nucleus.

OFT alignment defects in Hes1 mutant embryos have been independently observed by another group who, in addition, noted aortic arch artery abnormalities associated with a defective smooth muscle contribution at E11.5 (P. Scambler, personal communication).

As side-effects, the presence of NH4Cl in the growth solution slowed down the electrodeposition rate and resulted in closer packed and lower aspect ratio NWs, but having a higher degree of vertical alignment and less defective surfaces.

Alignment of the nucleotide sequence of defective clones permitted assignment of single dominant amino acid residues for binding to each monoclonal antibody.