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This defect of the study has to be corrected in future well-planned studies.
However, it was not possible to obtain uniformity in the subsample sizes according to age, consistent with our study design, and a major defect of the study was our failure to sample individuals < 17 years old, because the samples were obtained with the voluntary participation of the population, and if children are included, the consent of their parents is legally required.
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However, the defect of this study was the lack of an orthotopic human pancreatic cancer xenograft animal model to evaluate the in vivo contrast enhancement imaging efficacy of the CXCR-4-USPIO probe, and this issue will be our research direction in the future.
In addition, detailed information about recurrence was not available, which is a defect of this study, making the investigation of the relation between SDF-1 expression and recurrence unachievable.
Although the inquiry is widely expected to give Terminal 5 the go-ahead, the inquiry inspector, Roy Vandermeer, is understood to have been impressed by the evidence about the defects of the studies on which the government is relying.
In contrast, as the defects of this study, the follow-up examination is relatively short.
There was no observed change in severity (average dB loss) for the central defect of the 17 study participants who had a central defect at both baseline and randomization (mean 11.5dBB versus 6.7 dB at baseline and randomization, respectively; p = 0.09) after SFC adjustment.
For the remaining bone measurements, Student's t test revealed a statistically positive difference in the measurements carried out from the CEJ to the base of the bone defect, and the width of the bone defect in the study group (to a level of probability of 95%).
These results were mirrored in the untreated chondral- and osteochondral defects of the present study as seen in Table 2 and Fig. 3a and b.
As a result, no definite conclusion could be reached because of the design defects of the included studies and the small number of studies analysed in the meta-analyses.
The main defect of case control studies in the evaluation of the efficacy of screening is self-selection bias (Cole and Morrison, 1980).
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