This may reflect the more severe compound heterozygous frameshift and splice-defect nature of the mutations that make the product vulnerable to nonsense-mediated mRNA decay and subsequently affect the steady-state levels of LRPPRC protein.
He goes on to criticise Buffon's description of the crossbill's beak as "an error and defect of Nature, and a useless deformity" as "an erroneous and hasty conclusion".
The association between hypospadias and maternal age, both for younger and older women, might be explained as a "defect in nature's quality control" caused by a reduction of defensive maternal mechanisms that would be less efficient in the elimination of malformed fetuses in the mothers of hypospadias cases.
In the latter samples, only a partial passivation of both type of defects, whose nature is discussed, has been achieved.
The direct junction between the Pt NWs and graphene, as well as the defect-free nature of the graphene grown via chemical vapor deposition, enables the charge transfer from graphene to Pt in Pt-G.
Marinella details the defects of men, and in particular their evil motives, in order to support her positive argument for women's nobility, by demonstrating that the motives men have for denigrating women are ignoble, stem from defects of nature, and are thus evidence of the inferiority of men.
"It is a defect in my nature".
As he wrote in his 1851 "Confession," a "radical defect in my nature" has always been "a love for the fantastic, for unusual, unheard-of adventures which open up vast horizons and the end of which cannot be foreseen".
He has "a defect in his nature that travel has turned into a condition," and his eye is continually drawn to "tiny threatening details": shoe prints on a floor, a cracked brick wall, the blisters on his feet.
Software defect data in nature have a class imbalance because of the skewed distribution of defective and non-defective modules, so that conventional error functions of the neural network produce unbalanced FPR and FNR results.
A critical component of VPSC is the representation of the crystallographic nature (defect and dislocation movement) and orientation of the grains within the matrix material and the ability to account for the role of texture on deformation.
