Sentence examples for defect in the developmental from inspiring English sources

Alternatively, a defect in the developmental niche provided by the fetal liver for the maturation and enucleation of primitive erythrocytes may explain this phenotype [35].

To distinguish whether the abnormal response of Foxn1Δ/Δ T cells was directly due to the developmental defect in the thymus or the environmental defect in periphery, 4×106 sorted Ly5.1 wild-type peripheral T cells per mouse were retro-orbitally transferred into Foxn1Δ/Δ adult mice.

Interestingly, the developmental defect in the sma− cells was more severe than the defect in ampA− cells.

These results suggest that the developmental defect in the fiber SCW and production of thinner fiber cell wall in the im mutant was most likely due to the reduction of cellulose.

There was also progressive ossification of the neck defect in the 14 cases with developmental coxa vara (Fig. 7).

Our identification of genes whose expression is affected by exposure to maternal diabetes suggests that those genes could be involved in the developmental defects in diabetic pregnancies.

Therefore it is highly possible that mutations in ORC could potentially modulate a subset of gene expression via the alteration of chromatic contexts, which in turn results in the developmental defects seen in MGS.

During 2012, the IMPC estimated that ∼30% of mouse KO lines are embryonic or perinatal lethal and increasing efforts are being focused on examining embryos to determine mechanisms involved in the developmental defects.

Importantly, the most striking phenotype in female Rpn13−/− mice was a developmental defect in the ovaries.

LGR5 gene knockout in mouse results in neonatal lethality due to a developmental defect in the tongue [20].

Since Cnn functions in many diverse cellular processes, it was assumed to be impossible to examine a specific developmental defect in the photoreceptor.