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The association between T2 values and cartilage defect grade was investigated using a Spearman's rank correlation analysis.
Finally, the result is a complete loss of cartilage with widely open laying subchondral bone (cartilage defect, grade 4).
Also the correlation analysis revealed a stronger association of T2 values with cartilage defect grade after unloading, but generally smaller correlation coefficients as compared to the femoral condyle [12].
Cartilage volume Cartilage defect grade (grade 0 4) Bone marrow lesion (grade 1 2) Bone area T2 cartilage mapping Following arthroscopy and microfracture, all participants will complete online follow-up questionnaires at 1, 3, 6 and 12 months postarthroscopy.
In the present study as in the previous one on the cartilage layer above the posterior horn of the meniscus [12], we found increasing T2 values also with increasing cartilage defect grade.
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There were also a higher proportion of participants whose BMLs increased in those with baseline defect grades 2 to 4 versus those with defect grades 0 to 1 (b).
In this study, we compared T2 relaxation times at different cartilage layers, defect grades, and loading states with routine high-spatial-resolution MRI of the patella.
Mean T2 values for the deep, superficial, and global layer as well as the zonal variation were compared among defect grades (ANOVA, post hoc Duncan-test) and over time (Student's t-test).
Recently, different T2-values of healthy and repair cartilage [11] as well as a direct correlation of T2 values with cartilage defect grading [12] were shown in the unloaded state of the cartilage at the femoral condyle.
Whereas our study was rather confirmatory with respect to the impact of loading and the correlation of T2 values with defect grades, the observation of significantly increased T2-values in areas adjacent to focal defects despite normal morphology on high-resolution images is relatively new.
A relative consensus was observed regarding the differentiation of deep cartilage defects (grade IV).
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