Sentence examples for defect can be overcome from inspiring English sources

This growth defect can be overcome and cellular transformation promoted by the expression of defective, dominant negative alleles of p53 and of the mitotic checkpoint gene Bub1, both of which are known to induce chromosome instability.

While studies in both humans and mice demonstrate decreased T cell function in neonates, this defect can be overcome by the administration of strong adjuvants [4].

We showed previously that this defect can be overcome by activation of the M4 → TB synapse.

A central glenoid defect can be overcome by cancellous bone grafting, and the cortico-cancellous bone grafting is useful to bring a primary press fit of the baseplate during the reconstruction of anterior or posterior wall of the glenoid.

One scenario that might explain the genetic suppressor results is that the loss of TMG caps affects nucleolar architecture and function (Colau et al. 2004) such that the assembly or activity of Pol III is compromised at cold temperature, and this defect can be overcome, in part, by overexpressing either RPO31 or RPO26.

The phenotype is also variable within the pedigree we describe, as demonstrated by individual IV:2 who had a normal fundus appearance in one eye, indicating that the optic fissure closure defect can be overcome in the absence of SALL2 by the effects of other environmental, stochastic or genetic factors.

Interestingly, in that paper no apparent defects in developmental angiogenesis were reported suggesting either that the developmental defects that we report can be overcome in subsequent development or that additional defects arise from absence of ADAM17 in other cell types.

With GLP-1 this defect is modest and can be overcome with infusions that achieve higher GLP-1 levels.

113 Ube3am-p+ mice with a concomitant mutation in CaMKII that blocks inhibitory phosphorylation are indistinguishable from wild-type mice, 114 indicating the defect of E6-AP can be overcome with excess CaMKII activity.

However, filament formation depends on various stimuli and defects in hyphae formation can be overcome by appropriate stimuli.

Owing to the reason that more abundant information of the considered plants can be updated in due course and effectively exploited for each time instant, the conservatism of the obtained result is less than previous theoretical achievements and thus the main defect of those existing methods can be overcome to some extent in practice.