Setting aside defects attributable to other known causes, there were 849 cases of birth defects.
Musculoskeletal defects attributable to trauma or infection or as a result of oncologic surgery present a common challenge in reconstructive maxillofacial surgery.
No visual field defects attributable to the RON procedure were observed in any of the patients.
This 3-fold increase in mortality is consistent with the developmental defects attributable to OCRL deficiency leading to reduced viability.
A previous ERCP showed choledochal dilation, with an angle in the medium tract, and multiple small intraluminal filling defects, attributable to gallstones.
As mentioned above, we particularly focused on the molecular species whose level showed a significant alteration in the frontal but not in the occipital cortex because such a defect pattern may reflect the anatomical defects attributable to schizophrenia [ 22, 23].
Moreover, we have linked dendritic adhesion defects attributable to Ret to integrin and rac1 function featuring a novel and possibly conserved mode of action for Ret in dendrite development.
In Zebrafish, co-expression of the two proteins lead to developmental defects attributable to hypoplasia, malformation of the head, eyes and somites, a phenotype which is also compatible with enhanced, rather than decrease, p53 suppressive activity [ 15].
A number of MCCD patients have been previously reported to have consanguineous parents, which is associated with a wide variety of health and physical defects attributable to increased numbers of deleterious recessive alleles in the homozygous state.
Auricular defects and deformities include not only acquired defects attributable to trauma, burns, tumours, piercing defects, scars, and inflammation/allergies, but also congenital auricular malformations ranging from Grade I malformation (e.g., prominent ears) to Grade III malformations including severe microtia changes.
