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Interestingly, the migration defect also appears to be independent from a migration defect associated with mutations of the schizophrenia-associated protein, DISC1.
The defect associated with pol3-ct could result from a defective interaction between Pol δ and a protein involved in recombination.
Further, expression of these genes in Fe uptake-defective yeast mutants has been demonstrated to reverse growth defect associated with Fe uptake inability (Li et al. 2013; Pedas et al. 2008).
The severity of the associated COX mosaic defect varied widely, with a more pronounced histochemical defect associated with autosomal-recessive RRM2B mutations than autosomal-dominant mutations (Fig. 1).
Oxidative phosphorylation defect associated with primary adrenal insufficiency.
Microcephaly is considered the most severe birth defect associated with Zika.
Simhadri, S. et al. Male fertility defect associated with disrupted BRCA1-PALB2 interaction in mice.
Mangin, P. et al. Thrombin overcomes the thrombosis defect associated with platelet GPVI/FcRgamma deficiency.
Microcephaly is the most devastating birth defect associated with ZIKV-infected newborns.
This defect may represent the result of a sinus venosus defect associated with cor triatriatum.
Colombia has confirmed the first two cases of a rare birth defect associated with the spread of Zika.
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