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Most of these brainstem nuclei themselves receive input from the cerebral cortex, the cerebellar cortex, deep nuclei of the cerebellum, or some combination of these.
The reconstructed susceptibility map provided excellent contrast of iron-rich deep nuclei and white matter bundles from surrounding tissues.
It has been demonstrated that frequent migraine attacks may be associated with increased iron concentration/accumulation in deep nuclei which is involved in central pain processing.
New devices in development deliver electrical stimulation or pharmacologic agents locally to the epileptic focus or deep nuclei to modulate seizure activity.
Mossy fibers project directly to the deep nuclei, but also give rise to the following pathway: mossy fibers → granule cells → parallel fibers → Purkinje cells → deep nuclei.
Climbing fibers project to Purkinje cells and also send collaterals directly to the deep nuclei.
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Areas uninvolved in the human disease such as deep cerebellar nuclei and nucleus accumbens appeared resistant to PSI treatment in the transgenic mouse model.
The collaterals to the dentate nucleus constitute a reciprocal loop connecting the inferior olivary nucleus with the deep cerebellar nuclei (olivary-dentate-olivary loop, figure 1 B).
Deep grey nuclei include caudate nucleus, putamen, and thalamus in this study.
If the lesion involves the vestibulocerebellar output, then the vestibular nuclei correspond to the deep cerebellar nuclei.
A more moderate number of CTB-labeled neurons was observed in the ipsilateral subthalamic nucleus (Rico et al. 2010) and in the contralateral deep cerebellar nuclei.
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