Sentence examples for deep membrane from inspiring English sources

Furthermore, PS exposure in a target cell can be up regulated at the later stages of CT action (with still unclear molecular details) including deep membrane penetration, oligomerization, and pore formation.

Our results strongly suggest that stable complexes of BAK can only occur in the open conformation (B* as opposed to B), and that disruption of complexes with PBPs will yield free B*, which is assumed to be capable of further activation (deep membrane insertion, oligomerization, and autoactivation).

These observations suggest that C2AB membrane binding may involve some sort of favorable thermodynamic interaction between the two domains, which would allow the C2AB tandem to overcome barriers to deep membrane insertion experienced by individual domains.

The larger AD10 values are attributed to a major HFP population with deep membrane insertion and HFP contact with D10 H nuclei, and the smaller AD8 values are attributed to a minor population with shallow membrane insertion and HFP contact with D8 H nuclei.

After controlling for solvent accessibility, Kauko et al. (2008) found that TM sites have lower indel rates than EM sites for both helical and coil residues and that TM sites have lower amino acid substitution rates than EM sites for coil residues, which comprises only 7% of all sites within the deep membrane core.

Syp1 is among the first proteins to arrive, but it departs from the endocytic site before formation of a deep membrane invagination and scission, which coincide with the arrival of Bzz1 and Rvs161/167 at the site (Weinberg and Drubin, 2012).

However, intermediates possessing a membrane-contacting C1A or C1B domain [(IV) and (VI) have been directly observed in this study] can switch between a shallow or deep membrane-penetrating state, yielding ensembles that display multiple diffusion constants: fast and slow arising from shallow and deep penetration of the C1 domain into the bilayer, respectively.

Second, fluorescence measurements similarly demonstrate a deeper membrane penetration of Syt1 C2B in the context of the C2AB tandem relative to the isolated domain, even when the C2AB tandem is mutated so that C2A cannot bind Ca2+.

Mtch2 promotes tBid binding to MOM by enhancing a conformational change of tBid that leads to deeper membrane insertion and is required for its Bax activation capability (Supplementary Figure S3 and Shamas-Din et al)., whereas Bax may be reversing this conformational change.

Induction of fat cell differentiation made actin organization change from mostly stress-fibers (Fig.  4a1, b1) to a cortical network surrounding wide, deep plasma membrane invaginations (Fig.  4a2), previously described as 'caves' (Parton et al. 2002), protruding into the perinuclear region.

In Gram-positive bacteria, the cell wall consists of a deep layer of membrane, consisting of linear polysaccharide chains, and the Gram-negative bacteria possess a slender layer of membrane [26].