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But in recent years, a new technique has been developed to target a small, lens-shaped area deep inside the brain, called the subthalamic nucleus.
It's been pioneered in Parkinson's disease, where a small group of neurons buried deep inside the brain starts to die and the electrodes take over their job.
Deep inside the brain, in a region called the hypothalamus (right above where our optic nerves cross) the internal clock is ticking.
The tumor lies deep inside the brain, appearing as a tangled white splotch amid the ripples of grays in the cranial scan.
But it also causes side effects, like involuntary muscle contractions and dizziness, perhaps because turning on electrodes deep inside the brain also activates extraneous circuits.
Tonegawa said: "It is possible that in the future some technology will be developed to activate or inactivate cells deep inside the brain, like the hippocampus or entorhinal cortex, with more precision.
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Go deep inside the Daisy with THUMP.
As it moves deeper inside the brain, the contrast decreases and the noise is reconstructed instead.
Phobias are essentially errors of recording, byproducts of traumatic events committed to memory through the amygdala and lodged deep inside the reptilian brain.
We are, of course, deep inside the business brains of the holiday industry.
Deep brain stimulation revealed that as the rats chirped, areas deep within the brain associated with positive feelings were activated.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com