Sentence examples for deep annotation from inspiring English sources

As apparent from Figure 4A, over 80% of drug target GPCRs presented deep annotation levels and scored between 8.5 and 10.0.

As increasingly deep annotation of the human genome accumulates, it may be possible to detect additional associations between lentiviral integration and particular bound proteins, potentially allowing identification of host cell factors operating in the absence of LEDGF/p75.

Furthermore, we located numerous nsSNPs using a deep annotation process, which could be candidate genetic markers for predicting genetic variations in traits of interest.

When two or more QTL co-located on the same genomic region, a unique overlap QTL interval was considered and a deep annotation of its sequence was done in terms of genes and SNP markers.

Deep annotation of the intestinal mRNA sequence space is still missing, although microarray studies suggested a high complexity of region-specific expression patterns [ 22, 23] and disturbances of intestinal homeostasis are linked to a broad variety of diseases (e.g. infections, idiopathic inflammatory bowel disease and intestinal malignancies) [ 24, 25].

The manual and deep annotations allowed pinpointing of the weaknesses of automatic annotations.

A draft genome sequence of Ciona intestinalis was reported in 2002 (Dehal et al. 2002), and deep annotations of genes encoded by the genome have been carried out since then (Satou et al. 2008).

We could show that the GCI scoring function mirrored an increase in genome annotation performed by the research community through a shift of score distributions to deeper annotation levels.

However, a deeper annotation revealed that these coffee GRPs contain 12 cysteines instead of the six cysteines of the aforementioned class II GRPs (Additional File 11).

Although deeper annotations (e.g. FANTOM, ENCODE) exist, we have chosen a design similar to a previous study [ 33] using a combination of RefSeq and ENSEMBL as standard gene databases to detect novel elements.

Denser genetic maps with deeper functional annotation are required to evaluate if genes with similar functions are clustered or not.