Unlike the ML approach, the least squares (LS) approach does not assume any characterization of the noise statistic affecting the observations; hence, it is deemed a suboptimal method [13].
A frequency based Likert scale was deemed a suitable method for scoring and a three or five point Likert was considered.
Positron emission tomography (PET) using florbetapir-F18 (AV-45) or Pittsburgh Compound-B-C11 (PiB) as radiotracers reflects fibrillar brain amyloid deposits and is deemed a reliable method to measure brain amyloid plaque burden [ 3, 4], but cost and availability of PET biomarker measures are drawbacks associated with this diagnostic strategy.
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Meta-ethnography has been deemed an effective method of synthesizing qualitative findings in a systematic way (Campbell et al., 2011) and has already been widely used to advance knowledge across the medical and social sciences (Hubbard, McLachlan, Forbat, & Munday, 2012; Malpass et al., 2009; Ring et al., 2011; Smith, Pope, & Botha, 2005).
Such a method is deemed to be necessary for reliable evaluation of features associated with HYPS, which could potentially improve the assessment of infantile spasms, which is of significant importance in the therapy, management and ultimately the success of the prescribed treatment.
This curve shows each methods TPR for a range of FPR, where a method is deemed to have ranked genes better than another at a given FPR if its TPR is higher.
Tissue probability-based AC was deemed a promising interim method for PET/MR AC until standardized, commercialized solutions become widely available.
Nevertheless, due to the small sample size at the cluster level, it was deemed a more appropriate method than the life table technique, and it has been validated as an accurate estimate compared with more traditional methods [35].
In order to be deemed trustworthy, a diagnostic method should have an acceptable level not only of sensitivity, but also of specificity.
