The term "retarded," for children deemed to have limited ability, comes from the early-20th-century practice of holding back (retarding) those who read below grade level.
Psychedelic drugs are deemed to have limited medical utility and accordingly they are extremely unprofitable as a class (at least in terms of FDA approved pharmaceuticals).
Thus at the time of release on to the market in October 2009 the safety experience of Pandemrix was deemed to be limited.
First, it can help ensure that our guiding idea of what it means to treat patients as persons can be inclusive of people who are deemed to have limited competence for decision making, including the intellectually disabled and mentally ill.
By 2030, many say, Europe needs a 55% emissions cut, with 45% of energy derived from renewables, if it is to meet a goal of cutting greenhouse gases by 80-95% in 2050 (the cut in rich-world emissions deemed necessary to limit the rise in global temperatures to below 2°C).
Specifically, the bill advocates: (i) charging the firms premiums for systemic risk; (ii) imposing higher capital and liquidity requirements; (iii) restricting proprietary trading activities if deemed necessary to limit risk; and (iv) forcing the issuance of contingent capital, which will bring back market discipline and shift some of the risk from taxpayers back to creditors.
Respondents answering yes to both these questions were deemed to have a limiting long term condition (LLTC).
Notably, increased expression of genes deemed to be 'growth limiting' by virtue of their consistent down regulation in immortal cell lines, was observed.
The first module comprised an eight-gene, upstream, methylerythritol-phosphate (MEP) pathway native to E. coli, the pathway in which the expression of only four genes (dxs, idi, ispD, and ispF) that deemed to be rate-limiting was modulated.
Although this is deemed to be rate-limiting to translation [ 12, 32], more general translational efficiency can also be measured by the adaptation of all the uORF's codons to the organism's tRNA pool using the translation adaptation index (tAI) [ 33].
