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It takes longer than a diagnostic breast MRI, and it is a special procedure, requiring dedicated targeting and sampling equipment as well as trained personnel.
Owing to a lack of dedicated targeting sequences, one might expect that the AtMDL1 and AtMDL2 proteins localize to the cytoplasm and/or the nucleus (because of passive diffusion).
In summary, this study explains how GC-1 reaches its intracellular destination without containing a dedicated targeting motif, expands our understanding of the role of rhodopsin in photoreceptor biology and extends the diversity of signaling proteins found in GPCR complexes to a member of the guanylate cyclase family.
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To optimise access, almost all clinic-based projects established dedicated, targeted centres inside or within close proximity to areas in which FSWs live and work [ 45- 50, 60, 75- 99].
To date, this information is not available, and it will require dedicated, targeted mixture exposure assessment strategies to fill this gap.
This finding exposes a need for managers of PHC centers to dedicate targeted programs to professional with transferrable skills, so as to successfully retain them within their institutions.
Today, that integration has gone live across Target's website, mobile web and in the dedicated Target registry app.
As a result, we are capable of following the uptake, retention and dissociation of a radioligand to its dedicated target region directly during the experiment.
To control confounding factors due to potential variations of the dedicated target protein, an assessment of associated hA3R expression levels was obtained using Eq. (7).
Moreover, we obtained an estimation of the associated hA3R expression levels in order to control confounding factors due to potential variations of the dedicated target protein density (6C).
Binding association of 0.7 nM [125I]-AB-MECA at ambient temperature to CHO-K1-hA3R cells (a) and to CHO-K1 cells, without the dedicated target receptor (b).
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