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The particular hell explored in "Detachment" is a public high school (every high school, the movie implies) somewhere in the New York metropolitan area, as seen through the sorrowful eyes of Henry Barthes (Adrien Brody), a dedicated substitute teacher.
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Experts argue, however, that even the most enthusiastic and dedicated school-leaver is no substitute for the real thing.
Although it's true that most of our listening now happens online, it's hard to argue that wading through MP3 blogs and podcasts is a substitute to a BBC radio station dedicated to alternative music.
However, advertising restrictions will be phased in over 24 months up until the end of 2008 for dedicated children's channels where the "ability to substitute revenues from food and drink advertising would be more difficult to achieve quickly".
Tough love, but nothing substitutes for hard work, perseverance and dedicated practice.
"Regulation can never substitute for people doing their jobs honestly, dedicated to serving their customers as the fiduciaries they are," he said.
However, in contrast to the monofunctional TPases, which are dedicated to their respective roles, the bifunctional synthases can partially substitute for each other, enabling cells to survive with only one of them (Yousif et al., 1985).
In this context, the project team decided that this dedicated part of land could then be used for biomethane production substituting an equivalent amount of natural gas to fulfil the energy demand.
Poems (London, 1930; second edn., seven poems substituted, London, 1933; includes poems and Paid on Both Sides: A Charade ) (dedicated to Christopher Isherwood).
Provides for a dedicated funding mechanism to pay the full, agreed incremental costs to developing countries to shifting to safer substitutes, establishing 147 National Ozone Units in those countries, and training local experts on how to phase out chemicals.
While most Canadians find him cute in an overly enthusiastic substitute teacher who will connect with the kids by rapping a soliloquy kind of way, there are entire lists dedicated to how hot non-Canadians think he is.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com