Super enhancers (enhancer clusters) that produce enhancer-transcribed RNAs in mouse ES cells have recently been associated with H3K27ac, TET1 and a decrease in DNA methylation level at pluripotency-dedicated loci [ 61].
According to one influential hypothesis, these regions, and in particular the horizontal segment of the intraparietal sulcus (hIPS), are the loci of a dedicated, domain-specific number system, subserving operations with both symbolic and nonsymbolic stimuli [3].
We identified a large number of XEN-specific X inactivation escapers, which indicates that a mechanism dedicated to the definition of loci resistant to the global Xp silencing is at play in XEN cells.
The impact of vertebrate Myc on snoRNA synthesis can also be observed at the so-called SNHG loci – genes that are dedicated to the production of snoRNAs, analogously to the Drosophila Uhg genes.
Interestingly, singular var gene activation is linked to locus repositioning into a dedicated perinuclear expression site (Duraisingh et al., 2005; Ralph et al., 2005; Marty et al., 2006; Voss et al., 2006; Dzikowski et al., 2007).
As part of our ongoing efforts dedicated to the identification of genes and loci controlling important fruit-quality traits in peach, we studied the genetic control of aroma production and its relationship to other fruit quality characteristics.
No statistically significant locus was detected by this dedicated genome scan (Fig. 2i), which confirmed that the global redistribution of H3K14ac in RM is not caused by one or few master genetic regulators.
Each of us carries four to five million single nucleotide polymorphisms, and the HLA locus, the chromosomal region most dedicated to distinguishing self from non-self, contributes more to this total than any other part of our genome [ 1].
You can learn about science fiction conventions in your area by doing an Internet search or through publications such as "Locus," "Science Fiction Chronicle," or other magazines dedicated to science fiction fandom.
