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For this reason, we believed that there was no need to define the strength of recommendations provided, as national and international dedicated guidelines already exist [1, 2, 3, 4, 5].
Dedicated guidelines from major professional organizations or support from hospital leadership are thus sorely needed to promote these social media avenues.
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This PQ tests could be considered part of method validation, which will be the subject of a dedicated guideline.
Conclusions Cerebral oxygenation was stabilised in extremely preterm infants using a dedicated treatment guideline in combination with cerebral NIRS monitoring.
In the UK, the National Institute for Health and Clinical Excellence (NICE) is the independent organization dedicated to guideline development (http://www.nice.org.uk/).uk/
In summary, the burden of cerebral hypoxia and hyperoxia was significantly reduced in extremely preterm infants monitored by NIRS and treated according to a dedicated treatment guideline.
19 A dedicated treatment guideline (see supplementary file) was available for the clinical staff, listing possible interventions to normalise an out of range rStO2.
Cerebral oxygenation can be stabilised in extremely preterm infants during the first three days of life by using cerebral near infrared spectroscopy (NIRS) oximetry monitoring combined with a dedicated treatment guideline.
Cerebral rStO2 monitoring and a dedicated treatment guideline 18 are the cornerstones of a brain oriented protection strategy, with the goal of reducing periods of deleterious imbalance between oxygen delivery and consumption.
Interventions Monitoring of cerebral oxygenation using NIRS in combination with a dedicated treatment guideline during the first 72 hours of life (experimental) compared with blinded NIRS oxygenation monitoring with standard care (control).
19 We designed a phase II trial to test the hypothesis that the burden of hypoxia and hyperoxia could be reduced by the combination of cerebral NIRS monitoring and a dedicated treatment guideline, and to demonstrate the feasibility of conducting a multicentre randomised clinical trial with a complex intervention in infants across Europe.
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