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The only active VSG in T. brucei is expressed from one of 15 dedicated expression sites, while the active MSG in P. carinii is expressed from one unique expression site [ 4, 5].
An adaptive explanation for the high and dedicated expression of Irga6 in hepatic parenchymal cells is therefore not yet available.
This could be achieved by either developing novel expression tools or generating dedicated expression strains in which the suspected epigenetic transgene silencing mechanism is inactivated.
The same procedure was used to clone partial digestion fragments of PCR from cDNA, coding for horse butyrylcholinesterase, except that a dedicated expression vector was used for ligation (manuscript in preparation).
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Speaker: Dr. Weigman brings more than 13 years of biomarker discovery research with genomics, with a majority of them dedicated to Expression Analysis (EA), a Q2 Solutions Company.
In this report, we describe a dedicated Pancreatic Expression database [ 2] aiming to overcome this restriction, and furthermore propose it as a generic model for the organization, integration and presentation of complex cancer research data.
The CH999 strain of S. coelicolor, with most of the actinorhodin cluster removed, was among the first designer strains developed as a "clean" host dedicated for expression of foreign natural product clusters.
Interestingly, singular var gene activation is linked to locus repositioning into a dedicated perinuclear expression site (Duraisingh et al., 2005; Ralph et al., 2005; Marty et al., 2006; Voss et al., 2006; Dzikowski et al., 2007).
We therefore believe that dedicated gene-expression profiling offers the most powerful method of identifying gene groups that correlate to nodular growth, thyroid dedifferentiation or malignancy, taking into account the potential contamination by other cell types such as activated lymphocytes.
These microarrays contain around 6,864 genes and are dedicated to gene expression studies in Caco-2 cell line as well as to gene expression signature studies of multiple tumors.
As time passed and technology shrunk, the expression "dedicated controller" came into vogue and was promptly supplanted by "embedded controller".
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