Sentence examples for dedicated antagonist from inspiring English sources
Using a combination of surface plasmon resonance and isothermal titration calorimetry, a high affinity interaction between SlrA and SinR but not between SlrA and SlrR was found, necessitating a reassessment of the role of SlrA as a dedicated antagonist of SinR.
While this reassessment would simplify the role of SlrA in the circuitry of the switch, the questions would arise as to why 2 dedicated antagonists are required and how the activities or functions of these 2 antagonists differ.
By over expression of noggin, a BMP antagonist, in a dedicated mouse model of joint ankylosis, we provided evidence for this hypothesis.
Despite the high number of drug-discovery programs dedicated to finding small-molecule MCH-R1 antagonists for the treatment of obesity and/or mood disorders, a very limited number of these have progressed into the clinic.
Melanin-concentrating hormone (MCH) is an attractive target for antiobesity agents, and numerous drug discovery programs are dedicated to finding small-molecule MCH receptor 1 (MCHR1) antagonists.
To evaluate the pharmacophores selectivity for their dedicated NR ligands, each "SBLB agonist selective pharmacophores" and "SBLB antagonist selective pharmacophores" combinations were screened against all the other NRLiSt BDB datasets of ligands.
Hence, the value of A3 antagonists as pharmaceutical tools is obvious and a dedicated PET tracer for in vivo visualization A3Rs would be of high value for clinicians as well as patients.
Each SBLB combination of agonist selective pharmacophores and antagonist selective pharmacophores was tested for its selectivity for their dedicated NRs ligands on all NRLiSt BDB datasets.
That McCaughey's antagonists now operate in acknowledgment of her status as a dedicated liar does not necessarily diminish her ability to spread falsehoods.
A cult, dedicated to the resurrection of the dark lord, serves as the game's antagonists.
