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The inhibition of the product of essential genes that are upregulated during CDI may require a smaller drug dose to generate an effective response, thus decreasing side effects.
Combined administration may offer superior hemostasis while decreasing side effects.
Higher doses of the drug can be delivered, increasing its cancer-killing abilities while decreasing side effects.
The nanoparticulate drug delivery systems can improve the quality of antibacterial treatment by decreasing side effects and reducing the frequency of dosing via prolongation of drug residence time [5].
Pharmacogenomics--the study of how genes affect responses to drugs--is becoming more important in drug-development research and clinical trials, with a view toward decreasing side effects and increasing the efficiency and efficacy of drugs in patients with the right genetic profiles.
IMRT has the ability to decrease the dose to critical structures, therefore decreasing side effects of radiotherapy, while providing adequate dose to the tumor [ 5].
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Targeting delivery to diseased focus, as well as decreasing side effect to metabolic organs, is the main aim of nanoparticle-based drug delivery system.
"If we could simply take these poisonous drugs more directly to the tumors, it would increase their effectiveness and decrease side effects," Bhatia said.
RATIONALE: Memantine may be able to decrease side effects caused by whole-brain radiation therapy.
The potency, selectivity, and decreased side effects of bioactive peptides have propelled these agents to the forefront of pharmacological research.
These findings may provide useful information for designing drug delivery systems, which may improve anticancer efficacy and decrease side effects.
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