Both antiseptic lavage solutions and physiologic salt caused cell death and decreased integrity in the mesothelial monolayer [7, 8].
The data showed that agonal factors and low pH correlated with decreased integrity of extracted RNA in two brain regions.
It is well known that mesenteric ischemia per se, regardless of the IAP, may lead to decreased integrity, increased permeability, bacterial translocation (BT), and the development of MOF [10 12].
We conclude that monolayer disruption, progressive loss of cell contacts, and decreased integrity of cell junctions induced by Podocalyxin is likely linked to its ability to induce the apical domain expansion that is associated with microvillus formation.
46 If decreased integrity of the BBB promotes seizure progression we hypothesized that mannitol treatment would enhance the severity of seizures in otherwise protected tPA −/− mice.
It is well known that mesenteric ischemia per se, regardless of the IAP, may lead to decreased integrity, increased permeability, bacterial translocation (BT), and the development of MOF [ 10- 12].
Finally, the underlying mesenchymal cells and the ECM appear to have decreased integrity compared to those underlying the DE of the control limb buds (Fig. 2D panels 12 and 11; supplementary material Fig. S2).
In bivalves, low pH results in significant changes to larval development (e.g. [ 14]), reduced shell deposition in most species (e.g. [ 15, 16]), decreased integrity of the shell [ 17, 18] and weakened attachment of byssal threads [ 19].
Mechanical ventilation-induced acute pulmonary edema lung injury was caused by the reduction in occludin expression, degradation of tight junctions, decreased integrity of the alveolar membrane, and increased alveolar membrane permeability.
