Sentence examples for decreasing dosage from inspiring English sources

Formulation considerations of a new drug delivery system include controlling the site of release of the active ingredient, maintaining drug level for a suitable time and decreasing dosage frequency.

Despite alloantibody presence in five patients, eight patients remain without the need for specific treatment and only sirolimus monotherapy in decreasing dosage.

By inspection of adult eyes, we observed that pigment expression decreased with decreasing dosage of Slbp (Figure 3A).

We used information on increasing or decreasing dosage only to continuously assess whether tablets were available.

Apoptotic responses were also decreased significantly with decreasing dosage of Trp53 in the hormone-stimulated mice (P < 0.05).

The average bursting pressure rose slightly with decreasing dosage of carprofen but did not differ significantly between groups.

NR2F2 encodes a pleiotropic developmental transcription factor, and decreased dosage of NR2F2 in mice has been shown to result in abnormal development of atrioventricular septa.

Dissection of this phenotype in zebrafish embryos revealed a complex genetic architecture: dosage perturbation of four genes (ASGR1, ACADVL, DVL2, and GABARAP) impeded neurodevelopment and decreased dosage of the same loci caused a reduced mitotic index in vitro.

Engineering of this binding site in BoNT/A leads to mutants with >3-fold increased potency, which can be exploited as new therapeutics with decreased dosage and thus might prolong the period until immune response in patients.

The high image quality ratings recorded for fast imaging opens other possibilities such as a combination of decreased dosage of the administered radiopharmaceutical and fast imaging, which is now accepted as a compromise in our current use of DMI.

In females, we observed a trend toward increased LOH with decreased dosage of Slbp (Figure 1B).