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In Figure 5, three cases of simulated interferograms with decreasing coherence and the corresponding results obtained by means of spatial sampling, DFT, and DWT, are shown.
When decreasing coherence by 10% steps gains significantly decreased (t-test, p≤0.001), independent from the presented direction.
With decreasing coherence levels gains declined significantly (t-test, p≤0.001) and at 50% coherence only a gain of 0.5 is reached.
With decreasing coherence of the stimuli swim reactions against the stimulus direction increased, until at a level of 40% coherence, both response types were equally present.
In some animals the number of resetting saccades dropped, whereas in other animals the number of resetting saccades remained quite constant and only amplitudes of eye movements decreased with decreasing coherence levels.
As expected gains decreased with decreasing coherence of the presented stimulus, but the thresholds reached in our study are amazingly low compared to studies with other species [7], [8] except primates [9].
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Taken together our observation of individual animals and the population analysis show that even stimuli containing less than 20% coherently moving dots can trigger an OKR, although the likelihood to trigger an OKR decreases with decreasing coherences.
Figure 5 Synthetic interferogram example with different levels of phase noise added corresponding to simulated decreased coherence values and noise mitigation results by spatial sampling, DFT, and DWT.
Conclusively, reversion of these inequalities, which characterizes decreased coherence for the mutant, prohibits its establishment.
Moreover, untreated patients showed decreased coherence and gain values in comparison to controls.
In patients treated with long-term nCPAP, we observed decreased coherence and similar gain values in comparison to healthy controls.
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