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"We know that in adults, decreasing cholesterol and giving some of those drugs decreases risk of heart disease or death.
It is not as massively effective as the statins at decreasing cholesterol; by itself it lowers cholesterol levels by 18%, according to previous studies.
Besides decreasing cholesterol concentrations, statins have multiple additional effects that might influence the host response during sepsis, including inhibition of proinflammatory cytokine release and endothelial cell activation, reduction of endothelial dysfunction and attenuation of coagulation activation [3 6].
She interacted with industry, assessing dietary intakes in small groups to test things such as increasing fecal mass and decreasing cholesterol levels for companies that wanted to see "what effect a new cereal... had on the gastrointestinal tract," she says.
Unregulated ARF6 activation attenuates the NPC phenotype at least in part by decreasing cholesterol accumulation and restoring normal sphingolipid trafficking.
We also evaluated the possibility of decreasing cholesterol levels in the cells through the inhibition of de novo synthesis of cholesterol.
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Decreased sterol absorption leads to decreased cholesterol and LDL cholesterol levels, accompanied by enhanced cholesterol synthesis and enhanced cholesterol catabolism.
It also decreased cholesterol and CL levels to increase apoptosis.
Morra, V. B. et al. Interferon-beta treatment decreases cholesterol plasma levels in multiple sclerosis patients.
Additionally, treatment with miR-7 decreased cholesterol efflux and increased cholesterol levels in THP-1 macrophage-derived foam cells.
In another recent paper, by Valenza et al., Huntington's disease has been shown to decrease cholesterol biosynthesis in nerve cells.
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CEO of Professional Science Editing for Scientists @ prosciediting.com