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In a sequential series of tumours with decreasing active TGF- β1 levels (ELISA), we also observed strongly decreasing nuclear staining pattern in the myofibroblasts.
In addition to decreasing active Akt, PIAs have pleiotrophic effects in cancer cells including p38 and AMPK activation, p21 and RhoB induction, cellular detachment and apoptosis.
Actually, synergistic action can exist in herbal medicine, decreasing active concentration of pure compound [38, 45].
The mutations were chosen to improve 2-ethyhexanoic acid production by decreasing active site volume, increasing active site hydrophobicity, and improving stereoselectivity.
This means that the quantity of catalyst required for the transformation of an inert electrode into an active one decreases strongly with decreasing active particle size.
Economists, among others, are concerned with population aging, claiming that current welfare models cannot survive because of the decreasing active labour force [15, 16, 17, 18, 19, 20, 21, 22, 23].
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Thus, the drop in TEP observed in Experiment 2 is most probably caused by a decrease in TER rather than by decreased active transport activities.
Compounds were designed to decrease active metabolite load: reducing MTP activity of likely human metabolites and increasing metabolite clearance to reduce exposure.
Interfering with this loop decreases active β-catenin levels, lowers ERK1/2 activity, blocks proliferation, and induces apoptosis in MDA-MB-231, BT474, SkBr3, JIMT-1, and MCF-7 cells.
The latter may be caused by Fe deficiency decreased active Fe content.
Initially, passive range-of-movement exercises were undertaken, and eventually, as the pain decreased, active exercises were encouraged.
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