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The phrase "decreases threefold" is correct and usable in written English.
It can be used to describe a reduction in quantity or value by a factor of three.
Example: "The company's profits decreased threefold after the market crash."
Alternatives: "reduces by two-thirds" or "drops to a third".
Exact(1)
Such doses are consistent with the results from the McGill Geriatric Lithium-Induced Diabetes Insipidus Clinical Study (Rej et al. 2014b) reporting that the lithium dose required to achieve a given serum concentration decreases threefold from middle to old age.
Similar(59)
After 6 months of treatment plasma CXCL13 decreased threefold to 48.1 pg/ml (26.9 pg/ml to 93.0 pg/ml), P <0.001.
Myc protein levels were more substantially decreased (threefold to fourfold) upon introduction of the Myc shRNAs [see Figure S1 in Additional file 2].
Quantitative PCR showed that the mRNA expression of Nell-1 in the gastric cancer tissues was decreased threefold compared with that in the normal tissues.
The most effective in inducing disorder in the hydrophilic region of the erythrocyte membrane is the apple extract, the GP value decreasing threefold with the highest concentration used 0.05 mg/ml.
Likewise, casualties per incident in Israel decreased threefold between 1975 and 1979, assumed by Adler et al. to result from smaller explosive charges used due to tighter security measures [ 25].
In patients with this clinical phenotype, known as latent autoimmune diabetes of adults (LADA), β cell function decreases about threefold faster than in type 2 diabetes [ 4].
Transcript levels of IPP1 decreased about threefold in the abf1 -101 ts strain in this experiment, and ARO3 transcript levels decreased approximately 1.6-fold.
After getting the result of the l p calculation, the transition from the IPEC to the IMC was found to be accompanied with increasing of the effective size of region heterogeneity, while at transforming from the IMC into the PEC Ag0 nanocomposites, effective size of heterogeneity decreased almost threefold (Table 1).
We found that Tipe2 mRNA level in T cells was decreased by threefold as early as 4 h after activation.
In VAD-treated mice, Cyp7α mRNA increased approximately twofold and Hmgr decreased approximately threefold, probably as a feedback reaction to the elevated plasma cholesterol concentrations.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com