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Sinsabaugh [ 45] reviewed that responses of phenol oxidase to N enrichment can differ by the types of ecosystem determined, as it decreases its activity in the forest and increases it in grassland or agricultural system.
Consequently, it is plausible that oxidation of GS decreases its activity.
GSK3β is constitutively active, but phosphorylation at its serine-9 site decreases its activity.
Long-chain NEFAs also have an antilipolytic effect that may be secondary to activation of AMPK which phosphorylates hormone-sensitive lipase and decreases its activity [ 11, 14, 15].
Disruption of these interactions by site-directed mutagenesis (R146A, E148A, R150A, Q189A, and K280A) makes the protein insoluble or greatly decreases its activity.
An enzyme inhibitor is a molecule that binds to an enzyme and decreases its activity.
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Our findings show that MPO activity is highly activated in HOCl-treated mice, and consequently, PTU administration decreased its activity in the lungs.
Reactive oxygen species, produced during the CR [ 9- 12] can oxidize thiol groups located inside the active site of mammalian δ-ALA-D [ 50, 51], decreasing its activity as observed here.
The unavoidable increase in acidity will coagulate the photocatalyst and decrease its activity.
Also, CNP decreased the contraction induced by 30 mM KCl, without decreasing its activity.
Furthermore, the presence of 10% water slightly decreased its activity, and this effect was reversible following the removal of water from the feed.
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