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Rodent and human studies show that adiponectin decreases in conditions of metabolic stress such as obesity and type-2 diabetes, while weight loss increases plasma adiponectin levels [47].
This result is consistent with the previous finding that the efficiency of the photosystem decreases in conditions of water deficiency.
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Experimental results show that specific contact resistance of Cr/ITO contact decreases in condition of depositing chromium thin films on ITO at higher RF powers.
There is also evidence that SIRT1 mRNA and protein levels are decreased in conditions of energy excess, including Type 2 diabetes and obesity35,36,37.
In left and right bending, flextion, and extention, the stability of spine was decreased in conditions of single staple and double staples.
It indicated that in left and right bending, flextion, and extention, the stability of spine 1 was decreased in conditions of single staple and double staples compared to normal condition (P < 0.05).
It has been proposed that the close relationship between increased adipocytes and decreased bone formation in conditions of bone loss like age-related osteoporosis [ 13, 14].
Most tumour cells share the peculiar feature of switching their metabolism towards aerobic glycolysis, i.e. they increase glycolysis and decrease oxidative phosphorylation even in conditions of high oxygen tension [ 13- 15].
Furthermore, we found that the absence of IGF1R caused a decrease left ventricular remodelling in conditions of sustained biomechanical stress, such as eccentric hypertrophy, thus accelerating the transition towards heart failure.
According to one report [ 8], gastric tonometry failed to accurately estimate the magnitude of the decrease in tissue pH in conditions of low perfusion (total and partial occlusion of the superior mesenteric artery); direct measurement of pH with microelectrodes was found to be more accurate.
Here, we have attempted to further understand the role of SIRT1 in pancreatic β-cells by determining whether enhancing its activity affects β-cell function in vivo in conditions of decreased β-cell function selectively mediated by fat.
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