Sentence examples for decreases in cell function from inspiring English sources
Decreases in cell function with age may also play a role; as noted above, fetal tissue exhibits better wound healing than older tissue.
This puts the remaining cell population at high risk for any further decrease in cell function or cell numbers.
Therefore, it is not known whether increases in insulin resistance and decreases in beta-cell function observed in OSA are related primarily to OSA or to the otherwise high prevalence of previously unrecognized concomitant prediabetes.
Activation of CB1 receptors is associated predominantly with a dampening down of neuronal excitability, whereas activation of CB2 receptors is associated with decreases in immune cell function, including attenuated cytokine release [ 9, 17].
This first detailed characterisation of human islet circadian oscillator opens the way for future studies that may perhaps link defects in these pathways with decreased beta cell function in type 2 diabetes.
While studies in both humans and mice demonstrate decreased T cell function in neonates, this defect can be overcome by the administration of strong adjuvants [4].
These findings are the first direct in vivo demonstration of a causal role for NADPH oxidase in the NEFA-induced decrease in beta cell function.
In concordance with these results, we have demonstrated that a more severe decrease in Treg cell function can be seen in MRL/ lpr mice compared to MRL/Mp mice.
However, in the medium term (3 weeks), all doses of tamoxifen ≥1 mg/25 g body weight result in a decrease in the number of basal and EpCAM+CD49b− luminal cells and a decrease in progenitor cell function.
The results of this study suggest that there is not necessarily an overall age-related decrease in beta cell function but may be observed only in the setting of IGT or frank diabetes.
One prominent theory is that a decrease in stem cell function over time plays a significant role in tissue aging, which ultimately manifests at the organismal level.
