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Lutein, a StarD3 ligand, decreases cholesterol efflux to ApoA-I and HDL, but genetic overexpression and knockdown of StarD3 does not alter cholesterol metabolism or insulin release.
Each of the selected chemicals decreases cholesterol in the lysosomal storage organelles of NPC1 mutant cells through one or more of the following mechanisms: increased cholesterol efflux from the cell, decreased uptake of low-density lipoproteins, and/or increased levels of cholesteryl esters.
► DGAT1 deficiency decreases cholesterol uptake and absorption in ApoE-null mice.
10.7554/eLife.08009.015 Figure 9. Ligand activation of LXR decreases cholesterol content in lipid rafts and increases membrane lipid mobility.
Studies in various animal species revealed that CR delays aging, decreases cholesterol levels and blood pressure [ 12].
Other candidates include CES1 (carboxylesterase 1), which decreases cholesterol ester storage in human macrophages and promotes cholesterol efflux (Ghosh et al, 2003).
Similar(44)
Decreased sterol absorption leads to decreased cholesterol and LDL cholesterol levels, accompanied by enhanced cholesterol synthesis and enhanced cholesterol catabolism.
"We know that in adults, decreasing cholesterol and giving some of those drugs decreases risk of heart disease or death.
According to the Agriculture Department Nutrition Database, lard is composed of 42percentt saturated fat (which may increase cholesterol levels in the blood) and 54 percent unsaturated fat (which may decrease cholesterol in the blood).
It also decreased cholesterol and CL levels to increase apoptosis.
They have ability to decrease cholesterol levels in the serum (Fernandez et al. 2003).
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CEO of Professional Science Editing for Scientists @ prosciediting.com