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The average hepatosomatic index (HSI = weight of liver × 100/total fish weight), an indicator of hepatomegaly, in the Group II fish reared in TSW was also significantly higher than that in the reference Group I fish, but decreased to control level in Group III fish following depuration.
Ceramide, a known mediator of PCD in multiple neural and nonneural tissues, increased at 2-3 h after KA intraperitoneal injection, and then decreased to control levels before increasing again from 12 to 30 h after injection.
However, the increase was significantly higher in the α-syn-neurodegeneration group (Figure 4A), where numbers gradually decreased to control levels at 8 15 weeks.
When endogenous JA synthesis was inhibited at the stage of highest nectar secretion by application of phenidone, nectar secretion decreased to control levels.
Liver Mmp9 expression increased significantly in fibrotic animals but decreased to control levels in cirrhotic ones.
Maximum capillary density was obtained only when VEGF level was restored to baseline and then decreased to control when fibres muscle reached normal cross-sectional area.
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There is a repeatedly confirmed paradox of caspofungin efficacy decreasing to control level when administered in higher doses in murine models [ 96].
In the late acute phase of disease (3 days after infection) the number of apoptotic cells decreases to control levels [ 21].
In the group with cumulative doses above 200 mSv the values had decreased to controls.
We found that treatment with the NO donor, sodium nitroprusside (SNP) induced a sustained elevation of intracellular calcium level ([Ca2+]i) followed by a decrease to control levels.
This second increase in pS6 immunoreactivity was found to peak at 42 days after injury, followed by a decrease to control levels as observed 119 days after injury.
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