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Adjunctive DEX decreased severity score, haloperidol use and diazepam dose within 4 h.
There was no correlation between the improvement in QOLIE-10 scores and the reduction in seizure frequency, decreased severity of seizures, or increased level of energy/alertness.
The current findings that decreased severity of symptoms in the acute phase predicted improved HRQoL and less impairment in work-related outcomes lends further support for the relation between disease activity and PROs.
An enriched home cage delayed onset of motor symptoms, decreased severity of the clasping phenotype, and reduced the loss of peristriatal cerebral volume in R6/1 mice [6].
Pathological assessment of tissues from end of life male mutant mice showed a decrease in tumor incidence, decreased severity of renal lesions, and a trend towards a decrease in age-related cardiac pathology.
Clinical scoring on day 12 showed that a significantly decreased severity of EAU was observed in AAV2.hIFN-αlow and AAV2.hIFN-αhigh treated groups when compared with PBS and AAV2.GFP injected controls (p<0.0001).
This latter result has provided significant insight into the timing of reinfection and the severity and duration of disease: as long as some level of pre-existing immunity remains, repeat infections are likely to be of decreased severity and duration when compared to initial infection.
There have been studies showing decreased severity and duration of chorea with prednisone therapy.
We recently observed decreased severity of antigen-induced arthritis (AIA) in leptin-deficient ob/ob mice.
E2 administration to Ovx females abolished progressive growth and decreased severity of AngII-induced AAAs.
This decreased severity in arthritis is associated with decreased synovial inflammatory cell frequencies and reduced splenic T-cell proliferation.
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