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As homology arm length was decreased, integration efficiency also decreased, and the oligonucleotides were integrated at a low efficiency of approximately 0.15% (Fig. 3B).
Paired recordings from neighboring newborn neurons confirmed that miR-132 knockdown resulted in decreased integration into the perforant path circuit.
Moreover, it was expected that BD participants would be more affected by a change in stance and the loss of visual input, manifested as increased sway area, reflecting decreased integration of sensorimotor information.
In accord with that, a recent in vivo study showed that the deletion of Pten caused hyperactivation of the PI3K/Akt/mTOR pathway downstream of IGF-1R, leading to aberrant neuroblast differentiation and decreased integration in the OB (Zhu et al., 2012).
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Both turbine modification (annulus area increase) and compressor modification (increase in the surge pressure ratio) enabled a continuous increase in power and efficiency with decreasing integration degree.
If drift were the sole or primary determinant of genetic variability levels and patterns of community interrelationships, then the early mission period pattern of decreasing integration should have continued throughout the seventeenth century.
Elimination of RAD1 reduces integration of an ARS-containing plasmid by 5- to 10-fold, whereas mus81 and yen1 mutations do not decrease integration.
The long BAC arms also function to decrease integration-site effects in transgenic cell lines or mice.
Therefore, compared with this number of modules, common chimps show decreased musculoskeletal integration (11 modules) and humans show increased musculoskeletal integration (only 5 modules).
By implementing a pulsed laser, gated detector system we have improved the signal detection and have generally decreased the integration time necessary to detect Raman signal from natural surfaces.
Results suggest stability in youth reports of home integration over time; however, children who were older at the time of study enrollment and youth who experienced placement changes during the period of observation experienced decreased home integration during the 18-month period.
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