Sentence examples for decreased half from inspiring English sources

Although their absolute number was decreased, half of the type B cells persisted for 1 year following exposure (Fig 1B and C).

Furthermore, FRAP analysis shows that the highly dynamic binding association of histone H1 with the chromatin fibre is altered, with a severely decreased half time of residence.

Surprisingly, this decreased half-life correlated with a higher avidity than that of IgG for murine FcRn.

Similarly, at the CAPER gene, WT cells showed half-lives ranging from 5.8 hours to 20.3 hours (Suppl. Fig. S6B - blue hatched line and Suppl. Table S1), while KD cells measured decreased half-lives of 2 to 4.8 hours (Suppl. Fig. S6B - red hatched line and Suppl. Table S1).

The addition of the ZF domain to KLF6-SV1 results in its nuclear localization and a markedly decreased half-life similar to wild type KLF6.

Several explanations can account for the decrease in Bmi1 signal intensity in SYT-SSX2 infectants observed on cellular extracts immunoblots and by indirect immunofluorescence; these include a decrease in the transcription of Bmi1, a decreased half-life of Bmi1 protein and a post-translational modification that impairs epitope recognition by the Bmi1 monoclonal antibody used in our studies.

As reviewed by Saerens et al and Harmsen et al, the advantages of VHH over monoclonal antibodies are many such as the rapid tissue penetration, recognition of hidden antigenic sites, but the lack of effector functions and the decreased half-life is a disadvantage compared to monoclonal antibodies [10], [30].

Further, ectopic Fbxo15 expression significantly decreased half-life (t1/2) of CLS1.

This result is consistent with the overall increase in protein synthesis rates (decreased half-lives) observed with aging (Fig. 1C).

Furthermore, the decreased half-life under acidic conditions will promote accelerated degradation and release in cells or tumor environment.

Immunocytokines provide increased half-life to cytokines, but the antibody moiety has a decreased half-life when compared with the non-fused protein.