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In contrast, GFP-CRN5 over-expressing U373 cells migrated with an increased velocity of 17.3 μm/h and a decreased directionality of 0.5; the overall gap closure was not significantly changed (Fig. 3d).
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Software-based analysis of video recordings showed a decreased 'total directionality' in PTZ treated flies compared to control, i.e., flies treated with normal food (NF).
The effects of the texture were: (1) friction could be decreased, and (2) frictional directionality could be obtained with a combination of asymmetric texture and softer materials.
While a conventional approach to reduce the CTE would involve an increase in lattice rigidity by increasing the bond strength, our strategy focuses on the reduction of driving force for thermal expansion by decreasing the bond directionality.
For example, if A= 1.326 µm and at wavelengths shorter than λ ~ 555 nm, the waveguide parameter is larger than V = 2.405, consequently new modes are coupled decreasing drastically the directionality value.
The tension between increased salience due to changing stimuli and the decreased salience due to the directionality of the change may have lead to the null result observed here.
Questionnaire data were analysed off-line to determine the nature of any alteration in pain or temperature responsiveness and its directionality (increased versus decreased), based on caregiver descriptions of patients' overt verbal and non-verbal behaviours.
A subset of Alu-SINEs however display decreased methylation suggesting a bi-directionality in the effects of CGGBP1 on CpG methylation on Alu-SINEs.
Taken together, it appears that the disruption of microtubules leads to the reduction of the preferential radial traffic based on the analysis of angle trajectories of directional CB1R GFP puncta, which is consistent with the decrease of directionality index in colchicine-treated astrocytes.
First, horseshoe bat calls are highly directional and thus a mismatch of the caller's head aim and the receiver's pinna directionality will result in a decreased perceived intensity.
Measurements performed under inhibitory PI3K conditions showed that while directionality was modestly to significantly decreased by 10 and 50 nM Wortmannin in control 3D matrices (19% and 18% with P = 0.0219 and < 0.0001, respectively), the inhibitor seemed to have no effect on directionality induced by tumor-associated 3D ECMs (26%and2525% with P = 0.6641 and 0.5551, respectively).
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