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Functional magnetic resonance imaging studies in patients with migraine reflect heightened sensory facilitation, decreased inhibition in response to sensory stimuli, and lack of or decreased adaptation to interictal stimuli [44].
This decreased adaptation was apparent throughout the entire movement.
A post-hoc analysis of the movement trajectories corresponding to low and high congruency indices further illustrated the decreased adaptation following difficult to categorize words.
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This pilot randomized controlled trial tested the effectiveness of two interventions used to decrease adaptation difficulties by (a) providing knowledge of resources that are relevant to the Hong Kong context or (b) enhancing personal resilience in immigrants to Hong Kong from Mainland China.
Note that in both Fig. 4e and f, the trajectory starts with negative slope (dw /dt < 0 while dV / dt > 0) reflecting the decreasing adaptation current.
One reason is that fitness in stressful environments can be low even for well-adapted individuals, leading to small population sizes that increase drift and inbreeding (Frankham 1995; Willi et al. 2006), which can further decrease adaptation and fitness (Falk et al. 2012).
Yet another recent study of adaptation in large yeast populations did not observe that the speed of adaptation decreased during adaption under conditions where multiple mutations were presumed to be pervasive, and found that variation in fitness was higher at higher Nμb, supporting the multiple mutation model of adaptation [ 9].
Interestingly, CHO balance progressively decreased during adaptation to reach a significantly negative value on day 15.
Similarly, the level of pleiotropy decreased during adaptation.
Emotional support within and outside families promoted family cohesion and marriage quality, depression decreased family adaptation, and instrumental support decreased anxiety of PWE.
The fact that type II neurons showing a strong carbachol-dependent decrease in spike-frequency adaptation switched their PRC type is consistent with the theoretical finding that decreasing an adaptation current can switch the type of bifurcation leading from rest to tonic spiking [2].
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