Sentence examples for decrease virus from inspiring English sources
It has been well established that IFV develops resistance to NAIs through two mechanisms: one, mutations in NA that decrease binding affinity to NAI drugs, such as the H274Y mutation in the current seasonal IFV; two, mutations in HA which decrease virus receptor binding affinity, thereby reducing dependence on NA [9].
Similarly, combined E1A and DNA polymerase silencing did not further decrease virus titers (Fig. 7A).
The authors probably mean a decrease in specific infectivity since all antivirals would be expected to decrease virus infectivity.
Previous expose to other IAV may not prevent infection but it may decrease virus replication, and in this way it may be associated with reduced clinical signs.
For the Ad5 mutant strain, siRNAs targeting the E1A, IVa2, and hexon mRNAs were evaluated, and the IVa2 mRNA-targeting siRNA was reported to most efficiently decrease virus production.
Also, although not consistently significant, higher titers of virus were detected from groups with a single swab where the swab was left in the vial during transport, suggesting that removing the swab may marginally decrease virus detection.
This was attributed to the effect of ion shielding, which at higher ionic strength decreased the electrostatic attraction between the viral particles and the sand surface and consequently decreased virus sorption.
That AT-130 successfully decreases virus production by increasing capsid assembly rate without disrupting capsid structure delineates a paradigm in antiviral design, that disrupting reaction timing is a viable strategy for assembly effectors of HBV and other viruses.
The results indicated that the selected siRNA's interfered with EHV-1 infectivity and were capable of decreasing virus spread to neighboring uninfected cells.
This is the first demonstration that Wolbachia can increase resistance to arbovirus infection resulting in decreased virus transmission in a native Wolbachia-mosquito system.
Similar results have been described for Rous sarcoma virus (RSV), where a protease-linked dimer results in premature viral processing in the cytoplasm of infected cells in conjunction with decreased virus production [6].
