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It is therefore important to test susceptibility of these probiotic bacteria to compounds that may render them ineffective or decrease their capability to perform.
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From the functional point of view, AQP1 silenced cells decreased their capability to migrate.
Although the number of Tregs is not decreased, their capability to suppress polyclonal or antigen-specific proliferation of T cells in vitro has been shown to be compromised in MS patients [6] [8].
A decrease of cyclin A protein levels in myoblasts would be expected to decrease their proliferative capabilities.
The downregulation of AFAP1L1 in osteosarcoma cells markedly decreased their invasion capability in matrix gels, and the ectopic overexpression of AFAP1L1 in immortalized human mesenchymal stem cells resulted in a significant enhancement of invasiveness.
Asphalt pavement roads are exposed to traffic loading and natural elements such as rain, sunlight and oxidation, which result in decreasing their relaxation capabilities and the initiation of cracks.
They were widely used before the 1940s, but their use decreased as their capabilities were exceeded by those of the airplanes.
The sperm-specific protein, Izumo, a member of immunoglobulin superfamily (IgSF) which is located on the sperm stimulates hamster to secrete high titer of Abs both in the genital tract and serum and further decreases their reproductive capability [ 4].
HTF, LA also showed their capability of decreasing the CCl4-induced leakage of lactate dehydrogenase (LDH), aspartate aminotransferase (AST), inhibiting the lipid peroxidation, HTF showed more significant activity.
High temperatures are known to decrease human capability of performing physical and intellectual tasks (Confalonieri et al. 2007), which in turn can increase the risk of traffic crashes.
The fact that a strain after being desiccated reiteratively does not either increase or decrease its recovery capability suggests that neither selection nor adaptation were operating on it.
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