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Antidepressants are, however, known to decrease the risk of relapse [11].
Interventions to decrease the risk of relapse should be considered, including the possibility of maintenance immunotherapy and/or planned DLI.
The extension of paroxetine maintenance treatment from 12 to 24 months did not seem to further decrease the risk of relapse after medication discontinuation.
Using Cox's proportional hazards regression modelling we found an increase in cell density to decrease the risk of relapse for all three cell types.
Staging of primary breast cancer is performed to determine prognosis and to select adjuvant therapies, which decrease the risk of relapse and death.
These inhibitors could therefore be tested either in combination with initial chemotherapy or to eradicate residual disease after remission obtained with conventional treatment to decrease the risk of relapse.
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Targeting the primary (intestinal) niche by decolonization may be a valuable approach to decrease the risk of relapsing infections and to reduce transmission of ESBL-producing enteric pathogens.
Therefore, adjuvant treatments decreasing the risk of relapse are warranted.
Systemic chemotherapy for operable breast cancer significantly decreases the risk of relapse and death (EBCTG, 1998a, 1998b).
In these patients, interferon substantially decreased the risk of relapse by 25%, the risk of developing distant metastasis by 31%, and the risk of death by 31%.
18 Meta-analysis of pooled data of published trials indicates that CBT may also contribute to decreasing the risk of relapse over 12 24 months, suggesting that its benefits might extend beyond the acute phase of treatment.
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