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However, incubation with 5′-AMP failed to decrease the recruitment of NF- κB to these inflammatory gene promoters directly.
High doses of vitamin E (800 IU/day) can decrease the recruitment of monocytes to endothelim and cause decrement in oxidized LDL and the level of various plasma interleukines [ 22, 24].
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From this position, Nrf2 decreases the recruitment of the RNA polymerase II (Pol II) to the IL-1β gene and hereby negatively regulates IL-1β expression6.
Genetic invalidation and pharmacological inhibition of EGF-R significantly decreased the recruitment of immune cells within the peritoneal cavity following LPS injection (respectively, −65 and −42 %, P < 0.05).
Alternatively, L. casei decreased the recruitment of pathogenic CD8+ effectors into the skin at the site of challenge.
Cyclopamine significantly decreased the recruitment of BM-derived cells into the xenografts by 60% as compared with control tumors (Figure 3A).
Finally, chromatin IP (ChIP) analysis of human SCLC cells demonstrated that treatment of capsaicin decreased the recruitment of activator E2Fs, namely E2F2 and E2F3, to proliferative promoters like cyclin E, TS, cdc25A and cdc6.
Overexpression of ABI1/ABI2 in the presence of pUL135 resulted in increased recruitment of ABI by UL135, yet it decreased the recruitment of WAVE2.
Due to this regulation, depletion of KLF17 decreases the recruitment of Smad3 to its target gene promoters by reduced SBE/DNA Smad complex formation.
MMF-induced reduction of the expression and glycosylation of some adhesion molecules decreases the recruitment of lymphocytes and monocytes to sites of inflammation and graft rejection [ 50].
Pre-treatment with an inhibitor of [Ca2+]m uptake, Ru360, also decreased the recruitment of Drp1 to mitochondria, but had no effect on Drp1 protein levels.
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