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Moreover, hydroxyapatite coated on traditional orthopedic implants using plasma spray is not known to decrease the functions of fibroblasts (a cell well known to contribute to fibrous tissue encapsulation which can decrease orthopedic implant efficacy).
However, antibiotics used during therapy decrease the functions of the immune system.
The influences of P-gp and BCRP in the transport of [H]nifurtimox, were tested using four drugs that have previously been shown to decrease the functions of these transport proteins (Table 1).
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Her research shows that women taking hormone replacement therapy have an increased risk of dry eye, perhaps because estrogen may decrease the function of the meibomian glands.
Firstly, chronic hypoperfusion, which has been demonstrated in TgPAC-Notch3R169C mice [ 17], may decrease the functioning of ion pumps involved in ionic homeostasis, leading to intramyelinic oedema.
MSCs decrease the function of DC to secrete IL-12, which is important to promote an effective cellular immunity by activating and differentiating T cells[ 45].
Our results indicated that simulated microgravity increased the functions of CaL channels and ryanodine-sensitive Ca2+ releases in cerebral VSMCs, whereas, simulated microgravity decreased the functions of CaL channels and ryanodine-sensitive Ca2+ releases in small mesenteric VSMCs.
The hinge enhanced the functions of CARs against certain antigens while decreasing the functions of other CARs.
However, when electrophysiological experiments were performed at 35 °C in HEK 293 cells, PMA decreased the function of these receptors.
Furthermore, inhibition of AKT decreased the function of NF- κB, which is capable of transcriptional regulation of the BCL-2 gene [ 25].
DOI: http://dx.doi.org/10.7554/eLife.03502.007 10.7554/eLiFigure02.008 Figure 3 figure supplement 1. Decreasing the function of the core components of the SET1/MLL complex leads to a reduction in type II neuroblasts.
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