Exact(6)
Her research shows that women taking hormone replacement therapy have an increased risk of dry eye, perhaps because estrogen may decrease the function of the meibomian glands.
MSCs decrease the function of DC to secrete IL-12, which is important to promote an effective cellular immunity by activating and differentiating T cells[ 45].
Although it is currently unknown whether these polymorphisms increase or rather decrease the function of these regulators of muscle mass, molecular analysis and interrogation of other data might provide important information.
Importantly, our previous studies have demonstrated that some protease-reactive monoclonal IgG aCL can interfere with the inactivation of thrombin by antithrombin and decrease the function of plasmin and activated protein C [ 22, 23, 29].
Possible inhibition of the autoimmune response by type I IFNs could occur via increased concentration and activation of STAT1 mediated by the type I IFNs, which would decrease the function of STAT4, at least in part due to competition between STAT1 and STAT4 for binding to the IFNAR (29, 30).
Stress isn't just an emotion; it has physical repercussions, and chronic stress can negatively affect your immune system.Stress strains the body's resources, which can decrease the function of your immune system.
Similar(54)
However, antibiotics used during therapy decrease the functions of the immune system.
Firstly, chronic hypoperfusion, which has been demonstrated in TgPAC-Notch3R169C mice [ 17], may decrease the functioning of ion pumps involved in ionic homeostasis, leading to intramyelinic oedema.
However, when electrophysiological experiments were performed at 35 °C in HEK 293 cells, PMA decreased the function of these receptors.
Furthermore, inhibition of AKT decreased the function of NF- κB, which is capable of transcriptional regulation of the BCL-2 gene [ 25].
DOI: http://dx.doi.org/10.7554/eLife.03502.007 10.7554/eLiFigure02.008 Figure 3 figure supplement 1. Decreasing the function of the core components of the SET1/MLL complex leads to a reduction in type II neuroblasts.
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