There are no data on a dose response relationship between the size, the number, or the severity of the treated pathology and the corresponding magnitude of the increase in effectiveness or decrease in the adverse outcomes that were defined in the present systematic review.
Antibiotic treatment is reported to decrease these adverse outcomes although the existing evidence is of poor quality.
This procedure might have had decreased the adverse perinatal outcome and the events of vaginal delivery in the theatre for patients scheduled for emergency caesarean section (CS).
The adverse outcomes include decreased birth weight, decreased cord blood cytokines levels (both TH1 and TH2), increased collagen deposition in airway and alveolar walls, abnormal lung function at birth, and suppressed ventilatory responses to postnatal hypoxia (Sekhon et al. 2002; Ueda et al. 1999).
With decreased heart rate variability as the adverse outcome, negative associations between HRV and particulates were strongest for the smallest size fraction studied [ 33] (PM0.3 1.0); [ 34] (PM0.02 1).
Greater awareness of these risks amongst health care professionals might decrease the chances of adverse outcomes in those admitted to the ICU; awareness may also guide more appropriate emergency treatment for those who are critically ill, which may include not undertaking certain medical treatments that will put the patient at risk of further decline or death.
At the time the study was conceived, many believed that limiting antiviral exposure would decrease adverse outcomes, but the opposite was observed.
Targeting lower tidal volumes (6 to 8 ml/kg PBW) appears to decrease the incidence of adverse outcome, even without ARDS [ 65], and would appear to be reasonable in this population [ 22], as would a reduction in the respiratory rate during periods of minimal pulmonary artery blood flow.
A randomized controlled trial should be performed to clarify whether vitamin D supplementation can decrease adverse outcomes.
A secondary goal was to identify practice and patient characteristics associated with better medication documentation in order to inform future interventions to decrease adverse outcomes from medication errors.
