For example, in striatum, applications of DA decrease the activity of spontaneously active neurons to a greater extent than that of glutamate-stimulated neurons[6].
During inflammation, elastase release is increased while its in-activation is decreased, because oxygen radicals decrease the activity of its natural inactivator α1-antitrypsin.
Similarly, drugs that block a rise in intracellular Ca2+, such as -type Ca2+ channel antagonists, decrease the activity of calpains and result in the indirect activation of autophagy, likely by preventing the degradation of Beclin-1 and Atg-related proteins.
Therefore reduced levels of TXNIP would decrease the activity of PTEN, allowing an increase in the amount of PIP3 available to activate signaling in the AKT/mTOR growth pathway [94].
In contrast, S100A9 alone was previously shown not to activate phagocytes and, when it forms a complex with S100A8, to decrease the activity of this S100 protein [ 11].
The flying-ball governor remains an elegant early example of a negative feedback control system, in which the increasing output of the system is used to decrease the activity of the system.
Thus, a cascading effect will also decrease the activity of various other ATP-dependent efflux pumps.
Sulfur addition does decrease the activity of all the noble metal catalysts.
The presence of additional resistance mechanisms may further decrease the activity of Pip/Taz against ESBL-producing organisms.
These results show the first evidence that styrylquinolines decrease the activity of ABC multidrug transporters in C. albicans.
The increase of treatment temperature and pre-reduction can decrease the activity of catalyst for CH4 combustion.
