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TCDD is also known to decrease testosterone levels in adult male rats.
Statins could potentially decrease testosterone levels by reducing the availability of cholesterol for androgen synthesis.
Hyperprolactinemia is known to cause hypogonadism and decrease testosterone levels [ 59].
Even further, inhibitors of mTOR decrease testosterone levels in humans [ 42- 44].
In men, stress may suppress spermatogenesis, decrease testosterone levels and change testicular blood flow.
These results could indicate that dioxin-like compounds decrease testosterone levels in the blood and consequently interfere with the secretory function of the seminal vesicles or prostate.
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PETER GRAY, an anthropologist at the University of Nevada, Las Vegas, on a study finding that fatherhood decreases testosterone levels.
Researchers have found that high blood levels of a certain dioxin commonly found in the general male population may be associated with decreased testosterone levels and a not necessarily beneficial inhibition of prostate growth.
Men who are obese are also at increased risk of fertility problems, since excess body fat is associated with decreased testosterone levels.
The long-term implications of the role of fatherhood on decreasing testosterone levels are important to study ("Fatherhood Cuts Testosterone, Study Finds, for Good of the Family," front page, Sept. 13).
Therefore, the decreased expression of steroidogenic enzymes and StAR protein concerned in testosterone synthesis might be primarily related to the decreased testosterone levels as a result of BPA treatment.
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