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These findings may provide useful information for designing drug delivery systems, which may improve anticancer efficacy and decrease side effects.
Recently, alendronate became available as an oral solution to be administered once weekly (70 mg) in order to decrease side effects and maximize absorption.
Serotonin 1A receptor (5-HT1AR) agonists have emerged as valuable supplements to l-DOPA therapy, demonstrating that they can decrease side effects and enhance motor function in animal models of Parkinson's disease (PD) and human PD patients.
Progress in the aerosol delivery of drugs has been spurred by the significant benefits, including ease of use, patient comfort, greater selectivity of effect, and the potential to decrease side effects.
In 2014, Sepehri et al. determined the cytotoxic effect of HAS-SN38 nanoparticles on HT29 cells and showed that HAS-SN38 nanoparticles cause an increase in SN38 stability and decrease side effects due to the targeted treatment (Sepehri et al. 2014).
This method can allow a prompt detection of mood episodes (Grof et al. 1993), and possibly allow intermittent treatment, with lithium salts, for example, in those patients with a classical type of bipolar illness, which will decrease side effects and improve compliance.
Similar(34)
Afterwards, the DOX was released more slowly from CNTs-incorporated mats than that from the neat PLGA nanofibers, indicating the CNTs could effectively protect drug molecules from premature leakage, which was beneficial to decrease side effect of anticancer drugs.
The inhibition of the product of essential genes that are upregulated during CDI may require a smaller drug dose to generate an effective response, thus decreasing side effects.
Combined administration may offer superior hemostasis while decreasing side effects.
Patients may therefore benefit from decreased side effects during therapy and possible increased therapeutic efficacy.
Therefore, the combined administration of Kampo decreased side effects compared to the use of Western-style medicines alone.
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