Sentence examples for decrease profoundly from inspiring English sources

The only issue appeared with the use of targeted therapy, namely trastuzumab and bevacizumab, which decrease profoundly the CTC count: some reports suggested that this decrease might impact its prognostic value [ 8, 9].

On the other hand, when we treated with PI3Kinase inhibitors, Akt and mTOR phosphorylations were decreased profoundly (Fig. 2A).

When treated with JAKinase inhibitors, STAT3 phosphorylation and associated proliferation factors involving cell growth and CDK1, CDK2, Rex1, Nanog, and RUNX3 expression was decreased profoundly (Figure 3A and 3B, 3C).

Of these cells, the relative quantity of vimentin and E-cadherin co-expressing cells decreased from day 0 (77.9%) to day 7 (41.3%) and day 21 (10.3%); similarly, vimentin and CK8/18 double-positive cells decreased profoundly from day 0 (71.3%) to day 7 (48.3%) and day 21 (9.2%) (Figure 5A) (P<0.05A.

However, mortality will have decreased profoundly, partly because of new therapies and partly because we will understand the pathophysiology better.

Delayed gastric emptying decreased profoundly initial appearance of meal-derived glucose in the systemic circulation in conjunction with increased splanchnic glucose sequestration.

Whereas CMAP amplitudes decreased profoundly in the sepsis group (ratio of the prolonged time = -33.3%), CMAP amplitudes were much less decreased in the sham group (ratio of the prolonged time = -0.7%).

The objective of this study is to investigate the potential of open-source (OS) technologies in an educational setting, given the combination of economic constraints affecting all educational environments and the ability of OS design to profoundly decrease the cost of technological tools and technological innovation.

Coincidently, Sorrentino et al. screened a library containing 650 FDA-approved compounds and found that statins which are inhibitors of HMGCR (HMG-CoA reductase) could profoundly decrease YAP/TAZ nuclear localization (Sorrentino et al., 2014).

Although our treatment did not profoundly decrease proteinuria, KIM-1 did reach the normal range in 50% of patients.

Lewis et al. showed that in the human and pig heart, stimulation of the left vagus nerve can profoundly decrease contractility of the left ventricular myocardium, independent of its braducardic effect [ 54].