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A major gross side effect that was encountered with rolipram treatment was a significant decrease of weight gain, which is probably responsible for at least a part of altered alveolarization.
However, this decrease of weight gain was likely due to exposure-related stress (i.e., the restriction in the nose-only chamber for 6 hours; see Supplement 2).
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The decreasing of weight gain and feed utilization efficiency in fish fed with D2 could be due the low concentration of n-6 facidsacins in this diet (16.54%) compared to D3 (19.76%).
This prednisone-induced decrease in body weight and reduction of weight gain in mdx mice has also been noted in previous studies [8], [9].
Rodents exposed to PFOS have experienced adverse developmental outcomes, including decreased rates of weight gain and delayed lung maturation (Grasty et al. 2003; Lau et al. 2003).
Very recently there has been a report that rats vaccinated with ghrelin can produce neutralizing antibodies to the hormone and that this is associated with decreased rates of weight gain (Zorrilla et al., 2006).
Multivariable logistic regression on gaining ≥5 Kg provided similar results, i.e. that older vs. younger participants and those living in couple vs. alone had, respectively, a 62%9595% CI: 0.28-0.51) and a 27%9595% CI: 0.62-0.86) decrisked risk of weight gain, while current vs. never smokers had a 63% increased risk (95% CI: 1.35-1.95).
[ 18] Healthy physical activity levels among older women can act to decrease the amount of weight gain experienced during menopause and may attenuate the accumulation of adipose tissue in the upper and central body regions after menopause.
In males, CST did not affect adverse outcomes of IDM hypoglycemia, diabetic ketoacidosis, and weight gain, but CST decreased the incidence of weight gain (P =.05) and hypoglycemia in females (P =.03).
This decrease suggests a slower pace of weight gain between 9 and 20 months compared with the period between birth and 9 months in ALSPAC girls.
Positive effects included a faster-than-anticipated rate of weight gain, decreased hepatosplenomegaly, and lowering of the total IgG and IgM concentrations toward more normal values.
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