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The significant increase of exercise behavior and the substantial decrease of waist circumference and borderline decline of BMI at follow up visit in the HIP compared to the non-HIP group in our current study.
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The reduction of waist circumference and decrease of BMI was also significantly stronger in the intervention group (see Table 2).
Our significant result of weight loss within the intervention group was accompanied by simultaneous decrease of the waist circumference.
From baseline to 6 months, 47% of participants in the SfW group had a decrease of their waist circumference, 34% were stable, and 19% had an increase.
Furthermore, the daily reduction of waist circumferences was significantly larger during liraglutide treatment than before liraglutide introduction, suggesting that liraglutide effectively decreased visceral fat adiposity.
In the initial analysis, both the SfW and the control group decreased in waist circumference (WC) between baseline and 3 months, but in the sensitivity analysis the SfW group was observed to have a decrease of the mean waist circumference of 2.2 cm (95% CI: -2.8; -1.6) while the control group had an increase of 1.2 cm (95% CI: 0; 2.4).
However, the intervention group had a mean decrease in waist circumference of 1.9 cm, whereas the control group had an increase of 0.2 cm, potentially reflecting the effects of lifestyle changes.
We also observed a decrease in waist circumference of approximately 2 cm in the tofogliflozin groups, suggesting that tofogliflozin may improve metabolic disorders.
The reduction in the metabolic syndrome appears to be a result of the decrease in waist circumference and increase in HDL-C (Després et al. 2005a).
26 Bolinder et al also examined the secondary endpoints of waist circumference, which decreased −1.52 cm.
For waist circumference a decrease was defined as a decrease of at least 2 cm, a stable waist circumference was defined as a change between - 2 cm and 2 cm, and an increase was defined as 2 cm increase or more.
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